Dysarthria: an unusual side effect of tricyclic antidepressants.

Dysarthria: an unusual side effect of tricyclic antidepressants.

four days and, before this, diazepam 5-10 mg thrice daily and nitrazepam 5 mg at night for seven months. Although fits may occur when larger doses of benzodiazepines are withdrawn, their occurrence after withdrawal of therapeutic doses of this kind is extremely rare.3 A review of published reports has shown only one other case of fits possibly induced by viloxazine; this also occurred during a ...

Tricyclic antidepressants.

Tricyclic antidepressants.

Correspondence BRiTISH 301 Tricyclic Antidepressants SIR,-I am worried by one sentence in the article on tricyclic antidepressants (13 April, p. 102): "Jaundice, which is very uncommon , is of the cholestatic type similar to that found in chlorpromazine." This is misleading. Jaundice is one of the more frequent side-effects reported from imipramine and imitrip-tyline, the most widely used membe...

Acrocyanosis as a side effect of tricyclic antidepressants: a case report.

Acrocyanosis is probably the most unusual side effect of tricyclic antidepressant drugs. In this paper, we report a 10-year-old boy with primary enuresis nocturna and attention deficit hyperactivity disorder who developed two episodes of acrocyanosis, the first of which was after imipramine treatment and the second after desipramine usage. We also review the possible pathogenesis of acrocyanosi...

Pharmacokinetics of Tricyclic Antidepressants

This review, together with Part 1 (Gun. Chem. 26: 5-17, 1980), summarizes progress in measurement of tricyclic antidepressants in biological fluids and the application of the methodology to Clinical practice. For many of the older drugs and for all of the new-generation antidepressants, further studies are required to delineate the precise relationship between plasma concentration and clinical ...